VIROFIT
CAPSULES

Natural
Synbiotic
Natural
Bioenhancer
Herbal
Extracts
Capsule
Formulation
Animal / Human Pharmacological Activity

VIROFIT is a novel yet
innovative development

VIROFIT to prevent and control COVID-19, MERs, SARs and Influenza. VIROFIT can be used on all types of patients. VIROFIT medicine will be support not only COVID pandemic it will be support post-COVID time for initial stage of all antiviral, anti-inflammatory diseases and strengthen immune system.

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Benefits

Proof of Concept

SR. No. Ingredients Clinical Indications
1
Nigella sativa Seed Extract

Inhibit pro inflammatory mediator like IL-1Beta,
IL-6 and TNF-Alpha¹,².

2
Polygonum cuspidatum
Root Extract

ACE II inhibitor³,⁴ and Inhibition of spike S1 Protein³

3
Curcuma longa Rhizome
Extract

TMPRSS2 inhibitor ⁵⁻⁷ and Sialic acid Inhibitor ⁸⁻¹¹

4
Sophora japonica
Flower Extract

Zn Ionophore ¹² and Inhibitor RNA dependent
RNA Polymerases Enzyme ¹³⁻¹⁶

5
Moringa oleifera Leave Extract

Anti-inflammatory effect by inhibition of
NF-κB pathway Activation ¹⁷⁻¹⁹

6
Glycyrrhiza glabra Root Extract

Gut health²⁰

7
Cichorium intybus Root Extract

Natural prebiotic²¹

8
Piper nigrum Fruit Extract

Bioavailability enhancer²²,²³ and Alkylating agent²⁴

Refferences

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[13] Ono K, Nakane H, Fukushima M, Chermann JC, Barré-Sinoussi F. Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. Eur J Biochem 1990;190:469–76 oi:10.1111/j.1432-1033.1990.tb15597.x.

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[15] Yao C, Xi C, Hu K, Gao W, Cai X, Qin J, et al. Inhibition of enterovirus 71 replication and viral 3C protease by quercetin. Virol J 2018;15:116. doi: 10.1186s12985-018-1023-6.

[16] Ahmed-Belkacem A, Guichou J-F, Brillet R, Ahnou N, Hernandez E, Pallier C, et al. Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention. Nucleic Acids Res 2014;42:9399–409. doi:10.1093/nar/gku632.

[17] Su S, Li X, Li S, Ming P, Huang Y, Dong Y, et al. Rutin protects against lipopolysaccharide-induced mastitis by inhibiting the activation of the NF-kappaB signalling pathway and attenuating endoplasmic reticulum stress. Inflammopharmacology 2019;27:77–88. doi:10.1007s10787-018-0521-x.

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